Author

Shuangshuo Jia

Sheng Jing Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Yue YangiD· 2 shared Changping Niu· 1 shared Gang Yao· 1 shared Jiabao Liu· 1 shared Liang CheniD· 1 shared Lunhao BaiiD· 1 shared Weiming Zhang· 1 shared Yang WangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Yue YangORCID

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2 papers

Recent·Most cited

Cell BiologyCellular and Molecular Life SciencesPeer-reviewedMar 23, 2026

CILP from Cartilage Intermediate Zone Inhibits Hyaline Cartilage Fibrosis and Chondrocyte Ferroptosis via Keap1-Nrf2 Axis in Early Osteoarthritis Exercise Therapy

Shuangshuo Jia, Zhehan Hu, Zihan Li…·Yue Yang

The paper investigates how moderate exercise in early OA rats upregulates CILP in the cartilage intermediate zone, inhibiting fibrosis and ferroptosis via the Keap1-Nrf2 axis.

9 citationstop 1%

ratscRNA-seq

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Cell BiologybioRxivNov 19, 2023

PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

Shuangshuo Jia, Yue Yang, Jiabao Liu…·Lunhao Bai

This study shows that PPARγ enhances exosome biogenesis in fibroblast-like synoviocytes via the ESCRT pathway, and these exosomes containing ANXA1 alleviate osteoarthritis by inhibiting ERK phosphorylation and chondrocyte apoptosis.

DOI 10.1016/j.jot.2025.06.008

humanscRNA-seq

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