Author

Shuqi Luo

Case Comprehensive Cancer Center

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Alexandar L. HanseniD· 1 shared Chen WuiD· 1 shared Han WangiD· 1 shared Hung‐Ying KaoiD· 1 shared Matthias BuckiD· 1 shared Sichun YangiD· 1 shared Wangfei YangiD· 1 shared Wenwei ZhengiD· 1 shared

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Alexandar L. HansenORCID

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1 paper

Recent·Most cited

BiophysicsNaturePeer-reviewedJan 8, 2025

Phosphorylation modulates estrogen receptor disorder by altering long-range hydrophobic interactions

Zhanwen Du, Han Wang, Shuqi Luo…·Sichun Yang

This study shows phosphorylation at Ser118 of the estrogen receptor's disordered N-terminal domain alters long-range hydrophobic interactions, leading to conformational changes that activate transcriptional function.

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protein structurebiophysical modeling

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