Cell BiologybioRxiv
GTSE1 tunes microtubule stability for chromosome alignment and segregation through MCAK inhibition
Shweta Bendre, Arnaud Rondelet, Conrad Hall…·Alexander Bird
This study shows GTSE1 inhibits MCAK to regulate microtubule stability, affecting chromosome alignment and segregation, and links GTSE1 expression to chromosomal instability in cancer.
DOI 10.1083/jcb.201606081