Author

Sidae Lee

The University of Texas at Austin

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Molecular Biology· 1

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Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

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Alan M. LambowitziD· 1 shared Jennifer L. StamosiD· 1 shared Mo GuoiD· 1 shared Seung Kuk ParkiD· 1 shared Wantae KimiD· 1 shared Yan ZhangiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperMolecular Biology

Alan M. LambowitzORCID

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1 paper

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 29, 2025

Structural basis for the evolution of a domesticated group II intron-like reverse transcriptase to function in host cell DNA repair

Seung Kuk Park, Mo Guo, Jennifer L. Stamos…·Alan M. Lambowitz

This study determines the structural basis for how a domesticated reverse transcriptase evolved to function in DNA repair by revealing key structural adaptations in its apoenzyme and DNA synthesis complexes.

6 citations

bacteria (other)DNA methylation

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