Wantae Kim

This study identifies a noncanonical role of TEAD in DNA repair, showing it can be targeted to overcome chemoresistance in tumors.

The paper introduces NitrOFF, a fluorescent biosensor for real-time nitrate detection in mammalian cells, showing it responds to nitrate with a turn-off fluorescence mechanism.

This study determines the structural basis for how a domesticated reverse transcriptase evolved to function in DNA repair by revealing key structural adaptations in its apoenzyme and DNA synthesis complexes.

This study shows how phosphorylation of the CTD regulates condensate formation and alternative splicing across species.

The paper develops a biosensor-AI system to engineer E. coli for efficient production of amaryllidaceae alkaloids, achieving improved titer and reduced byproducts.

This paper evolves highly specific and sensitive biosensors for alkaloids using a combined screening and selection approach, enabling improved microbial production of therapeutic plant metabolites.