Systems BiologyPLOS ONEPeer-reviewed
Transcriptional bursting explains the noise-versus-mean relationship in mRNA and protein levels
Roy D. Dar, Sydney M. Schaffer, Siddarth S. Dey…·Leor S. Weinberger
The paper re-examines HIV LTR mRNA and protein expression data, finding that noise scales inversely with mean expression, supporting the inverse correlation between noise and mean.
DOI 10.1371/journal.pone.0158298