BiochemistrybioRxivPreprint
Multi-stem-loop constrained library enables accelerated SELEX for aptamers with superior kinetics and affinity
Qinuo Wang, Yuhan Zhao, Siyi Zhao…·Long Hong
This paper develops a multi-stem-loop constrained library to accelerate SELEX for aptamers, resulting in candidates with superior binding kinetics and affinity in fewer rounds.
DOI 10.1101/2025.11.27.690911