BiophysicsbioRxivPreprint
Modeling Reveals How Direct-Acting Antivirals Redirect HBV Capsid Assembly Pathways to Noninfectious Products
Layne B. Frechette, Smriti Pradhan, Farzaneh Mohajerani…·Michael F. Hagan
The paper uses a kinetic Monte Carlo model to simulate how CAMs alter HBV capsid assembly, revealing mechanisms that lead to noninfectious structures.