Author

Srilakshmi Premachandran

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Loza F. TadesseiD· 1 shared M. B. McDonaldiD· 1 shared Shruthi Ravichandran· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Loza F. TadesseORCID

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1 paper

Recent·Most cited

BiophysicsACS SensorsPeer-reviewedSep 12, 2026

Nucleic acid turnover and lipid remodeling distinguish T cell activation and exhaustion states via label-free Raman spectroscopy

M. B. McDonald, Srilakshmi Premachandran, Shruthi Ravichandran, Loza F. Tadesse

This paper uses label-free Raman spectroscopy to distinguish T cell activation and exhaustion states with high accuracy, identifying nucleic acid turnover and lipid remodeling as key features.

DOI 10.1021/acssensors.6c02987

humanmicroscopy & imaging analysis

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