Author

Stephanie M. Kyle

Emory University

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alicia C. Walker· 1 shared Amanda EngstromiD· 1 shared David J. KatziD· 1 shared Dexter A. Myrick· 1 shared M. Jordan RowleyiD· 1 shared Rohitha A. Moudgal· 1 shared Yu BaiiD· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperNeuroscience

Alicia C. Walker

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1 paper

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedNov 2, 2020

The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration

Amanda Engstrom, Alicia C. Walker, Rohitha A. Moudgal…·David J. Katz

This study shows that pathological tau sequesters LSD1, leading to neurodegeneration, and that modulating LSD1 can mitigate tau-induced damage in a mouse model.

39 citations

mouseexperimental assay

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