Author

Sun YuDong

University of Michigan

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Biochemistry· 1

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Approach:statistical model· 1

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H. ZhangiD· 1 shared Jifeng ZhangiD· 1 shared Xiaoqiang HuangiD· 1 shared Y. Eugene CheniD· 1 shared Yoichi OsawaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBiochemistry

H. ZhangORCID

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1 paper

Recent·Most cited

BiochemistryACS Synthetic BiologyPeer-reviewedMar 6, 2026

Computational design of CYP102A1 variants for the biosynthesis of a next-generation antiplatelet drug DT-678

Sun YuDong, Xiaoqiang Huang, Jifeng Zhang…·H. Zhang

This paper designs CYP102A1 variants to biosynthesize the antiplatelet drug DT-678, showing improved catalytic activity and productivity with ascorbic acid protection.

4 citationstop 2%

proteomicsdeep learning

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