Cell BiologybioRxivPreprint
Anti-vitronectin single-chain variable fragment targeting the hemopexin-like domain decreases age-related macular degeneration indicators in ex vivo models of the retinal pigment epithelium
Jun W. Kim, SUSANNE R. MEYER, Ben Lopez…·Hyunsuk Min
The paper develops an anti-vitronectin antibody that reduces drusen accumulation and complement pathway activation in an in vitro model of age-related macular degeneration.
DOI 10.1101/2025.08.18.670968