Cell BiologyPLoS GeneticsPeer-reviewed
CED-5/CED-12 (DOCK/ELMO) can promote and inhibit F-actin formation via distinct motifs that target different GTPases
Thejasvi Venkatachalam, Sushma Mannimala, Yeshaswi Pulijala, Martha C. Soto
The paper identifies that CED-5/CED-12 can both promote and inhibit F-actin formation by acting as a GEF for Rac1 and a GAP for CDC-42/RHO-1 during different cellular processes.
3 citations