Molecular BiologyBioorganic & Medicinal ChemistryPeer-reviewed
In vitro and in vivo activity profiles of broad-spectrum bacterial ATP synthase inhibitors
Suzanne Chamberland, Audrey Larose, Guillaume Millette…·Pierre‐Luc Boudreault
The paper evaluates the antibacterial activity of tomatidine analogs against various bacterial strains, identifying TM-184 as effective against Gram-positive, Gram-negative, and multidrug-resistant bacteria, with in vivo efficacy in a mouse model.
DOI 10.1016/j.bmc.2025.118493