Author

Svenja Denker

University of Lübeck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Axel Kuenstner· 1 shared Carolin GragolliD· 1 shared Christian FrerkeriD· 1 shared Christoph KnosallaiD· 1 shared Derk FrankiD· 1 shared Elias RawishiD· 1 shared Hauke S. BuschiD· 1 shared Ingo Eitel· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Axel Kuenstner

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 7, 2026

Sphingolipid-Driven Lipotoxicity Promotes Calcific Aortic Valve Disease Through ER-Stress-NF-κB-EndMT Signaling and Is Therapeutically Targetable Through Serine Palmitoyltransferase Inhibition

Elias Rawish, Timo Rusack, Peter Ruben Letsch…·Christian Frerker

This study identifies ceramide-driven lipotoxicity as a driver of calcific aortic valve disease and shows that SPT inhibition can reverse disease progression in vivo.

DOI 10.64898/2026.10.07.757226

humanmouse

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