NeuroscienceNeuropsychopharmacologyPeer-reviewed
Synaptic control of DNA-methylation involves activity-dependent degradation of DNMT3a1 in the nucleus
Gonca Bayraktar, PingAn Yuanxiang, Alessandro D. Confettura…·Michael R. Kreutz
This study shows that synaptic activity controls DNA methylation by degrading DNMT3a1 via NMDAR-dependent neddylation.
27 citations