Cell BiologybioRxivPreprint
Abnormal shear stress induces ferroptosis in endothelial cells via KLF6 downregulation
Jingang Cui, Zhiyu Fan, Suoqi Ding…·Yongsheng Ding
This study shows abnormal shear stress induces ferroptosis in endothelial cells by downregulating KLF6, leading to reduced SLC7A11 and CoQ10 levels and increased lipid peroxidation.
DOI 10.1101/2025.09.10.675441