Author

T. A. Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

J. J. Park· 2 shared M. C. Hammond· 2 shared Z. F. Hallberg· 2 shared B. Nan· 1 shared C. H. Chan· 1 shared D. Bond· 1 shared G. Chen· 1 shared K. W. Doxzen· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

J. J. Park

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2 papers

Recent·Most cited

Second messengers and divergent HD-GYP enzymes regulate 3’,3’-cGAMP signaling

T. A. Wright, L. Jiang, J. J. Park, W. A. Anderson, G. Chen, Z. F. Hallberg, B. Nan, M. C. Hammond

This study identifies cAMP as an activator of GacB and cGAMP-specific phosphodiesterase PmxA, revealing cross-regulation between CDN pathways and predicting non-canonical HD-GYP enzymes.

bioRxiv · Apr 5, 2019Biochemistry

cGAMP signaling controls a transient surface-associated lifestyle

Z. F. Hallberg, C. H. Chan, T. A. Wright, P. J. Kranzusch, K. W. Doxzen, J. J. Park, D. Bond, M. C. Hammond

The paper shows that the GacA enzyme in Geobacter sulfurreducens specifically regulates cGAMP levels to control metal reduction genes, despite in vitro promiscuity, through a kinetic model and structural analysis.

bioRxiv · Dec 12, 2018Biochemistry