Second messengers and divergent HD-GYP enzymes regulate 3’,3’-cGAMP signaling
T. A. Wright, L. Jiang, J. J. Park…·M. C. Hammond
This study identifies cAMP as an activator of GacB and cGAMP-specific phosphodiesterase PmxA, revealing cross-regulation between CDN pathways and predicting non-canonical HD-GYP enzymes.