T. Abdalrahman

A constitutive model for the remodelling erythrocyte membrane skeleton during the active invasion by the malaria merozoite

This paper develops a constitutive model to simulate erythrocyte membrane damage during malaria merozoite invasion, showing reduced membrane stiffness with increasing phosphorylation.

Mathematical model for force and energy of virion-cell interactions during full engulfment in HIV: Impact of virion maturation and host cell morphology

This study develops a mathematical model to quantify virion-cell interactions during HIV engulfment, showing that localized membrane features and maturation affect viral entry.

In silico mechanics of stem cells intramyocardially transplanted with a biomaterial injectate for treatment of myocardial infarction

This study uses finite element models to analyze how biomaterial stiffness affects stem cell deformation in a rat heart after myocardial infarction.

Mathematical Model of Mechanosensing and Mechanically Induced Collective Motility of Cells on Planar Elastic Substrates

This paper develops a mathematical model to simulate mechanically-induced collective cell motility on elastic substrates and demonstrates its predictive capabilities for wound closure and cell behavior.

An analytical model describing the mechanics of erythrocyte membrane wrapping during active invasion of a plasmodium falciparum merozoite

This study develops a mathematical model to describe the mechanical forces and deformations during Plasmodium falciparum merozoite invasion of erythrocytes, showing how membrane phosphorylation reduces indentation work.

Intracellular mechanics and TBX3 expression jointly dictate the spreading mode of melanoma cells in 3D environments

This study shows that melanoma cell spreading in 3D environments depends on both cell stiffness and TBX3 expression, with different behaviors observed in soft versus stiff matrices.

In silico stress fibre content affects peak strain in cytoplasm and nucleus but not in membrane for uniaxial substrate stretch

The paper assesses how stress fibre content and substrate stiffness affect strain distribution in different cell regions using a finite element model.

An exploratory study on the role of the stiffness of breast cancer cells in their detachment from spheroids and migration in 3D collagen matrices

This study investigates how breast cancer cell stiffness changes during detachment from spheroids and migration in 3D collagen matrices, finding that decreased stiffness facilitates detachment and migration.

Micromechanical homogenisation of a hydrogel-filled electrospun scaffold for tissue-engineered epicardial patching of the infarcted heart

This paper uses homogenization techniques to model the mechanical properties of a hydrogel-filled scaffold for cardiac tissue engineering and predicts its impact on ventricular function.

Cytoskeletal Tubulin Competes with Actin to Increase Deformability of Metastatic Melanoma Cells

This study shows that metastatic melanoma cells have increased fluidity and cytoskeletal components, which enhance motility while reducing stiffness compared to earlier disease stages.