Author

T. Aung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Pathology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:cell type annotation· 4 Assay:imaging· 4 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:clinical cohort / trial· 1 Approach:deep learning· 1

Frequent Co-Authors

M. J. A. Girard· 6 shared X. Wang· 4 shared S. K. Panda· 3 shared T. A. Tun· 3 shared F. A. Braeu· 2 shared M. Baskaran· 2 shared M. E. Nongpiur· 2 shared M. Nongpiur· 2 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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6 shared papersBioengineering

M. J. A. Girard

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Author profile →

9 papers

Recent·Most cited

How Myopia and Glaucoma Influence the Biomechanical Susceptibility of the Optic Nerve Head

T. Chuangsuwanich, T. Tun, F. Braeu, C. Yeoh, R. Chong, X. Wang, T. Aung, Q. Hoang, M. J. A. Girard

This study compares biomechanical strain in optic nerve heads under different conditions across groups with varying myopia and glaucoma status, finding significant differences in strain levels.

bioRxiv · Dec 19, 2022 · PreprintBioengineering

The Structural Layers of the Porcine Iris Exhibit Inherently Different Biomechanical Properties

R. K. Y. Tan, S. K. Panda, F. A. Braeu, A. R. Muralidharan, M. E. Nongpiur, A. S. Y. Chan, T. Aung, R. P. Najjar, M. J. A. Girard

This study isolates porcine iris tissues and measures their biomechanical properties, finding the stroma more permeable and less rigid than the dilator muscle.

bioRxiv · Dec 11, 2022Bioengineering

Enhanced Complex Stability and Optimal JAK Geometry are Pivotal for a Potent Type III Interferon Response

T. Aung, C. M. Horvath, J. L. Mendoza

This study identifies that optimizing JAK-JAK geometry enhances type III IFN signaling potency by 2-3 logs, offering insights into cytokine signaling and therapeutic development.

bioRxiv · Sep 27, 2022 · PreprintCell Biology

Integrative deep learning analysis improves colon adenocarcinoma patient stratification at risk for mortality

J. Zhou, A. Foroughi pour, H. Deirawan, F. Daaboul, T. Aung, R. Beydoun, F. S. Ahmed, J. H. Chuang

This paper develops an integrative deep learning model combining image, clinical, and genomic data to improve risk stratification for colon adenocarcinoma patients, showing better performance than models using single data types.

bioRxiv · Jun 13, 2022Pathology

Differing Associations between Optic Nerve Head Strains and Visual Field Loss in Normal- and High-Tension Glaucoma Subjects

T. Chuangsuwanich, T. A. Tun, F. A. Braeu, X. Wang, Z. Y. Chin, S. K. Panda, M. Buist, N. Strouthidis, S. Perera, M. Nongpiur, T. Aung, M. J. A. Girard

This study examines the relationship between optic nerve head strains under IOP elevation and retinal sensitivity in glaucoma patients, finding stronger associations in high-tension glaucoma compared to normal-tension glaucoma.

bioRxiv · Dec 15, 2021Bioengineering

Changes in Iris Stiffness and Permeability in Primary Angle Closure Glaucoma

S. K. Panda, R. K. Y. Tan, T. A. Tun, M. L. Buist, M. Nongpiur, M. Baskaran, T. Aung, M. J. A. Girard

This study compares iris biomechanical properties between healthy individuals and PACG patients, finding higher stiffness and lower permeability in PACG.

bioRxiv · May 4, 2021Bioengineering

Hybrid Derivative of Cathelicidin and Human Beta Defensin-2 Against Gram-Positive Bacteria: A Novel Approach for the Treatment of Bacterial Keratitis

D. S. J. Ting, E. T. L. Goh, V. Mayandi, J. Busoy, T. Aung, M. Periayah, M. Nubile, L. Mastropasqua, D. Said, H. Htoon, A. Veluchamy, R. Beuerman, R. Lakshminarayanan, I. Mohammed, H. Dua

This paper develops a hybrid antimicrobial peptide (CaD23) from human-derived host defense peptides, showing high efficacy against Gram-positive bacteria and reduced antimicrobial resistance compared to amikacin.

bioRxiv · Apr 22, 2021Microbiology

Effect of Changing Heart Rate on the Ocular Pulse and Dynamic Biomechanical Behavior of the Optic Nerve Head

Y. Jin, X. Wang, S. F. R. Irnadiastputri, R. E. E. Mohan, T. Aung, S. A. Perera, C. Boote, J. B. Jonas, L. Schmetterer, M. J. A. Girard

The paper models how changes in heart rate affect ocular pulse and biomechanical properties of the optic nerve head, finding decreased pulse amplitude and increased stiffness with higher heart rates.

bioRxiv · Sep 16, 2019Bioengineering

Optic Nerve Tortuosity and Globe Proptosis in Normal and Glaucoma Subjects

X. Wang, H. Rumpel, M. Baskaran, T. A. Tun, N. Strouthidis, S. A. Perera, M. E. Nongpiur, W. E. H. Lim, T. Aung, D. Milea, M. J. A. Girard

The paper compares optic nerve tortuosity and globe proptosis between glaucoma and normal subjects using MRI, finding greater tortuosity in normal eyes during adduction and higher proptosis in glaucoma subjects in primary gaze.

bioRxiv · Aug 22, 2018Pathology