Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
K. E. Kishi, Y. S. Kim, M. Fukuda, T. Kusakizako, E. Thadhani, E. F. X. Byrne, J. M. Paggi, C. Ramakrishnan, T. E. Matsui, K. Yamashita, T. Nagata, M. Konno, P. Y. Wang, M. Inoue, T. Benster, , H. E. Kato
The paper presents the cryo-EM structure of ChRmine, revealing unique architectural features and provides insights into its conduction mechanism and potential for optogenetic applications.
bioRxiv · Aug 15, 2021Biophysics