Y. S. Kim

This study develops a microfluidic hPSC-based model to control biochemical and biomechanical signals during somitogenesis, revealing their roles in somite formation.

This study identifies an alternative splice variant of Drp1 in ovarian cancer that promotes metastasis and chemoresistance by altering mitochondrial dynamics.

This study uses holotomography and machine learning to classify functional immune states of human monocytes, achieving high accuracy in identifying hyper-inflammatory and immune-suppressed states.

The paper determines the cryo-EM structures of two K+-selective channelrhodopsins, revealing a unique mechanism for K+ selectivity distinct from canonical K+ channels.

This paper presents a label-free method for high-resolution volumetric imaging and analysis of mouse brain tissue with sub-micrometer spatial resolution.

This study examines the differential effects of low and high doses of pentoxifylline on RAW 264.7 cells using IP-HPLC, showing distinct impacts on proliferation, inflammation, and differentiation.

The paper shows NDR1 overexpression enhances pathogen resistance at elevated temperatures by maintaining immune signaling during ETI.

This study investigates how genome divergence and compatibility contribute to the stabilization of hybrid genomes in an allopolyploid plant species.

The paper presents the cryo-EM structure of ChRmine, revealing unique architectural features and provides insights into its conduction mechanism and potential for optogenetic applications.

This study shows that HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage independence in ovarian cancer cells.

This study shows viperin reduces cholesterol levels by inhibiting key enzymes in the biosynthetic pathway, though the exact mechanism remains unclear.

cytoNet analyzes cell communities in microscopy images to quantify spatial relationships and functional interactions, demonstrating applications in neuroscience and tissue biology.

This paper introduces a data-driven method for multiplexed microtomography using refractive index imaging to study endogenous subcellular dynamics without exogenous labels.

This paper develops a DNA vaccine encoding SFTSV antigens and adjuvants that provides complete protection in IFNAR knockout mice, while protein antigens alone fail to do so.

This study shows that SIRT3 activation is required for ovarian cancer cell survival and metastasis by regulating mitochondrial antioxidant defenses and metabolic changes during detachment.

The paper analyzes immune cell infiltration in six cancers, finding activated B cells correlate with reduced CD8 T cell infiltration and increased Treg cells, suggesting B cells may inhibit T cell activity.