Lung epithelial CYP1 activity regulates aryl hydrocarbon receptor dependent allergic airway inflammation
F. Alessandrini, R. de Jong, M. Wimmer, A.-M. Maier, I. Fernandez, M. Hils, J. Buters, T. Biedermann, U. Zissler, C. Hoffmann, J. Esser-von-Bieren, C. B. Schmidt-Weber, C. Ohnmacht
This study investigates the role of CYP1 family members and AhR in lung epithelial regulation of allergic airway inflammation, finding that CYP1B1 deficiency exacerbates inflammation.
bioRxiv · Sep 20, 2021Immunology