Dynamic High-Content Imaging Reveals Surface Exposure Of Virulent Leishmania Amastigotes In Infected Macrophages Undergoing Pyroptosis
T. Rosazza, H. Lecoeur, T. Blisnick, M. Moya-Nilges, P. Pescher, P. Bastin, E. Prina, G. F. Spaeth
This study shows that Leishmania-infected macrophages undergo pyroptosis, exposing amastigotes to the extracellular environment, which may aid parasite spread.
bioRxiv · Feb 3, 2020Immunology