Author

T. Bourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Fischer· 1 shared A. K. Mangalam· 1 shared A. M. Cameron· 1 shared A. Sugiura· 1 shared A.-C. Boschat· 1 shared C. Soudais· 1 shared D. L. Greenwood· 1 shared D. Laughton· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Fischer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation

S. Latour, N. Minet, A.-C. Boschat, R. Lane, D. Laughton, P. Beer, H. Asnagli, C. Soudais, T. Bourne, A. Fischer, E. Martin

The paper investigates the differential roles of CTPS1 and CTPS2 in cell proliferation, finding that CTPS1 is more critical for cell growth than CTPS2.

bioRxiv · Mar 29, 2023Cell Biology

MTHFD2 is a Metabolic Checkpoint Controlling Effector and Regulatory T Cell Fate and Function

A. Sugiura, G. Andrejeva, K. Voss, D. R. Heintzman, K. L. Beier, M. M. Wolf, D. L. Greenwood, X. Ye, S. K. Shahi, S. N. Freedman, A. M. Cameron, P. Foerch, T. Bourne, X. Xu, J. C. Garcia-Canaveras, , J. Rathmell

This study identifies MTHFD2 as a metabolic checkpoint that regulates T cell fate and function by promoting effector cells and suppressing regulatory T cells.

bioRxiv · Feb 3, 2021Immunology