Author

T. Bruno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Mengarelli· 1 shared B. K. Johnson· 1 shared C. Cortile· 1 shared C. Passananti· 1 shared D. Yang· 1 shared F. de Nicola· 1 shared F. Fabbretti· 1 shared F. Pisani· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Mengarelli

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Author profile →

2 papers

Recent·Most cited

A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies

D. Yang, I. Beddows, H. Tang, S. Cascio, S. C. McGonigal, S. Bai, B. K. Johnson, J. J. Powers, R. Acharya, R. K. Bao, T. Bruno, T. Soong, J. R. Conejo-Garcia, H. Shen, M. T. Bility, R. Buckanovich

This paper develops a humanized immune stroma PDX model to better reflect therapeutic resistance and patient response to immunotherapies.

bioRxiv · Jul 3, 2023 · PreprintCancer Biology

AATF/Che-1, a new component of paraspeckles, controls R-loops formation and Interferon activation in Multiple Myeloma.

T. Bruno, G. Corleone, C. Cortile, F. de Nicola, V. Catena, F. Fabbretti, S. Gumenyuk, F. Pisani, A. Mengarelli, C. Passananti, M. Fanciulli

This study identifies Che-1/AATF as a paraspeckle component that regulates R-loop formation and interferon activation in multiple myeloma, linking R-loops to disease progression and poor prognosis.

bioRxiv · Aug 4, 2021 · PreprintCell Biology