Cancer BiologybioRxiv
Distinctive desmoplastic 3D morphology associated with BRAFV600E in papillary thyroid cancers
M. Tarabichi, A. Antoniou, S. Le Pennec…·V. Detours
The paper describes a distinctive 3D morphology in BRAFV600E-mutated papillary thyroid cancers where tumor cells form a sparse mesh within a proliferative stroma, challenging traditional tumor growth models.