Author

T. Cole

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. West· 1 shared E. Xu· 1 shared H. Zhao· 1 shared Z. Liu· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

A. B. West

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1 paper

Recent·Most cited

LRRK2 and Rab10 Coordinate Macropinocytosis to Mediate Immunological Responses in Phagocytes

Z. Liu, E. Xu, H. Zhao, T. Cole, A. B. West

This study shows LRRK2 and Rab10 coordinate macropinocytosis in phagocytes, with LRRK2 phosphorylating Rab10 to block cargo recycling and promote signaling endosome maturation.

bioRxiv · Jan 30, 2020Cell Biology