Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice
C. Müller, L. M. Zidek, T. Ackermann, T. de Jong, P. Liu, V. Kliche, M. A. Zaini, G. Kortman, L. Harkema, D. S. Verbeek, J. P. Tuckermann, J. von Maltzahn, A. de Bruin, Z.-Q. Wang, V. Guryev, C. F. Calkhoven
This study shows that reducing C/EBPβ-LIP expression in mice delays age-related phenotypes and extends lifespan, suggesting therapeutic potential for age-related diseases.
bioRxiv · Jan 18, 2018Cell Biology