ATP binding facilitates target search of SWR1 chromatin remodeler by promoting one-dimensional diffusion on DNA
C. C. Carcamo, M. F. Poyton, A. Ranjan, G. Park, R. K. Louder, T. Dzu, C. Wu, T. Ha
This study shows ATP binding enables SWR1 chromatin remodeler to diffuse along DNA, facilitating efficient target search by sliding over DNA until encountering roadblocks.
bioRxiv · Jan 24, 2022Biophysics