Cell BiologybioRxivPreprint
Pharmacological and fasting-induced activation of SIRT1/LXRα signaling alleviates diabetes-induced retinopathy.
S. S. Hammer, C. P. Vieira, D. McFarland…·J. V. Busik
This study shows that activating SIRT1 signaling through fasting or pharmacology reduces diabetes-induced retinopathy by improving cholesterol metabolism, reducing inflammation, and preserving neural function.
DOI 10.1101/871822