BiophysicsbioRxiv
Proximity-assisted photoactivation (PAPA): Detecting molecular interactions in live-cell single-molecule imaging
T. G. W. Graham, J. J. Ferrie, G. M. Dailey…·X. Darzacq
This paper introduces PAPA, a method using rhodamine dyes to detect molecular interactions in live-cell single-molecule imaging by reactivating a fluorophore from a dark state when proximal to another.
DOI 10.7554/elife.76870