A viral ring nuclease anti-CRISPR subverts type III CRISPR immunity
J. S. Athukoralage, S. McMahon, C. Zhang, S. Gruschow, S. Graham, M. Krupovic, R. J. Whitaker, T. Gloster, M. F. White
This study identifies a viral anti-CRISPR enzyme that degrades cyclic tetra-adenylate, neutralizing type III CRISPR immunity in bacteria and archaea.
bioRxiv · Sep 24, 2019Biochemistry