Author

T. Gutmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

Frequent Co-Authors

U. Coskun· 2 shared B. Brankatschk· 1 shared C. Poojari· 1 shared I. Schaefer· 1 shared I. Vattulainen· 1 shared K. H. Kim· 1 shared M. Grzybek· 1 shared M. Strauss· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

U. Coskun

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2 papers

Recent·Most cited

Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain

T. Gutmann, I. Schaefer, C. Poojari, B. Brankatschk, I. Vattulainen, M. Strauss, U. Coskun

The paper reports the cryo-EM structure of the insulin receptor ectodomain with four insulin molecules, revealing two binding sites and a T-shaped conformation.

bioRxiv · Jun 21, 2019Biochemistry

Visualization of ligand-induced transmembrane signalling in the full-length human insulin receptor

T. Gutmann, K. H. Kim, M. Grzybek, T. Walz, U. Coskun

The paper visualizes how insulin binding changes the structure of the human insulin receptor, leading to autophosphorylation.

bioRxiv · Oct 23, 2017Biochemistry