Author

T. Hoogeboom

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. S. Athukoralage· 1 shared M. F. White· 1 shared S. Graham· 1 shared S. Grüschow· 1 shared

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2019-2019 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

J. S. Athukoralage

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1 paper

Recent·Most cited

BiochemistrybioRxivJun 12, 2019

Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence

S. Grüschow, J. S. Athukoralage, S. Graham…·M. F. White

This study shows that Mycobacterium tuberculosis uses a type III-A CRISPR system with a cyclic hexa-adenylate (cA6) signalling pathway and the Csm6 ribonuclease for immunity against mobile genetic elements, rather than DNA cleavage.

DOI 10.1093/nar/gkz676

bacteria (other)experimental assay

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