Author

T. J. Borges

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Murshid· 2 shared B. J. Lang· 2 shared K. Lima· 2 shared L. V. Riella· 2 shared S. K. Calderwood· 2 shared C. Bonorino· 1 shared E. Hui· 1 shared G. T. Ribas· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Murshid

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Innate extracellular Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors

T. J. Borges, K. Lima, A. Murshid, I. T. Lape, Y. Zhao, M. M. Rigo, B. J. Lang, S. S. Siddiqui, E. Hui, L. V. Riella, C. Bonorino, S. K. Calderwood

This study identifies Siglec-E and LOX-1 as receptors mediating extracellular Hsp70's inflammatory properties through their interaction on dendritic cells.

bioRxiv · Dec 1, 2023 · PreprintImmunology

Immune Response of Transplanted Kidney Tissues Assembled from Organoid Building Blocks

T. J. Borges, Y. Ganchiku, J. O. Aceves, R. van Gaal, S. G. M. Uzel, J. E. Rubins, K. Kobayashi, K. Hiratsuka, M. Tekguc, I. A. Rosales, G. T. Ribas, K. Lima, R. B. Gassen, R. Morizane, J. A. Lewis, L. V. Riella

This study transplants engineered kidney tissues made from organoid building blocks into mice with human immune cells to assess immune response and tissue integration, finding immune infiltration causes tissue injury similar to transplant rejection.

bioRxiv · Aug 26, 2023 · PreprintBioengineering

Extracellular Hsp90α Detoxifies β-Amyloid Fibrils Through an NRF2 and Autophagy Dependent Pathway

A. Murshid, B. J. Lang, T. J. Borges, Y. Okusha, S. P. Doshi, S. Yasmine, J. Clark-Matott, R. Choudhury, L.-H. Ang, M. Woodbury, T. Ikezu, S. K. Calderwood

This study shows eHsp90 reduces neuronal toxicity from f-Aβ1-42 by activating NRF2-mediated autophagy in microglia.

bioRxiv · Apr 16, 2021 · PreprintCell Biology