Author

T. Junne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

R. Suetterlin· 2 shared U. Jenal· 2 shared A. Hierlemann· 1 shared A. Kurmashev· 1 shared A. L. Swart· 1 shared B. J. Laventie· 1 shared B.-J. Laventie· 1 shared C. Forsyth· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

R. Suetterlin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transwell-based microphysiological platform for high-resolution imaging of airway tissues

A. Kurmashev, J. A. Boos, L. Swart, B.-J. Laventie, T. Junne, R. Suetterlin, U. Jenal, A. Hierlemann

The paper introduces a microphysiological platform for culturing transwell-based lung tissues, enabling high-resolution live-imaging of airway infections and tissue responses.

bioRxiv · Nov 22, 2023 · PreprintBioengineering

Goblet cell invasion promotes breaching of respiratory epithelia by an opportunistic human pathogen

A. L. Swart, B. J. Laventie, R. Suetterlin, T. Junne, X. Yu, E. Karagkiozi, R. Okujava, U. Jenal

This study shows Pseudomonas aeruginosa breaches lung epithelia by invading goblet cells, using T6SS for invasion and T3SS for cell death, leading to barrier rupture and infection spread.

bioRxiv · Aug 13, 2023Microbiology

A common mechanism of Sec61 translocon inhibition by small molecules

S. Itskanov, L. Wang, T. Junne, R. Sherriff, L. Xiao, N. Blanchard, W. Q. Shi, C. Forsyth, D. Hoepfner, M. Spiess, E. Park

This study identifies a common binding site for diverse Sec61 inhibitors and shows how they stabilize the plug domain to block protein translocation.

bioRxiv · Aug 11, 2022Biochemistry