Author

D. Hoepfner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Basler· 1 shared A. Itzen· 1 shared A. Waldt· 1 shared C. Forsyth· 1 shared C. Hedberg· 1 shared C. Pett· 1 shared E. Park· 1 shared F. Nigsch· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Basler

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A common mechanism of Sec61 translocon inhibition by small molecules

S. Itskanov, L. Wang, T. Junne, R. Sherriff, L. Xiao, N. Blanchard, W. Q. Shi, C. Forsyth, D. Hoepfner, M. Spiess, E. Park

This study identifies a common binding site for diverse Sec61 inhibitors and shows how they stabilize the plug domain to block protein translocation.

bioRxiv · Aug 11, 2022Biochemistry

Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis

R. Ungricht, L. Guibbal, M.-C. Lasbennes, V. Orsini, M. Beibel, A. Waldt, R. Cuttat, W. Carbone, A. Basler, G. Roma, F. Nigsch, J. Tchorz, D. Hoepfner, P. S. Hoppe

This study uses genome-wide CRISPR screening in human kidney organoids to identify novel regulatory mechanisms in nephrogenesis, including a new role for Jagged1 in controlling epithelial proliferation.

bioRxiv · May 26, 2021Cell Biology

Monoclonal anti-AMP-antibodies reveal broad and diverse AMPylation patterns in cancer cells

D. Hoepfner, J. Fauser, M. S. Kaspers, C. Pett, C. Hedberg, A. Itzen

The paper develops three monoclonal anti-AMP antibodies that detect AMPylation in cancer cells, revealing diverse and broad modification patterns.

bioRxiv · Jun 23, 2020 · PreprintBiochemistry