Author

T. Luke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

H. Wu· 3 shared C. Bausch· 2 shared E. Cottle· 2 shared E. Sullivan· 2 shared K. Egland· 2 shared T. Gilliland· 2 shared W. Klimstra· 2 shared A. Bui· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

H. Wu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

No evidence for enhanced disease with polyclonal SARS-CoV-2 antibody in the ferret model.

D. S. Reed, A. McElroy, D. Barbeau, C. McMillen, N. Tilston-Lunel, S. Nambulli, E. Cottle, T. Gilliland, H. Rannulu, J. Lundy, E. Olsen, K. O'Malley, M. Xia, A. Hartman, T. Luke, , P. Duprex

This study tests if polyclonal SARS-CoV-2 antibodies enhance disease in ferrets, finding no significant differences in symptoms or viral shedding between antibody-treated and control groups.

bioRxiv · Aug 19, 2023 · PreprintMicrobiology

Finding the LMA needle in the wheat proteome haystack.

D. Vincent, A. Bui, D. Ram, V. Ezernieks, S. Shahinfar, T. Luke, S. Rochfort, N. Rigas, J. Panozzo, H. Daetwyler, M. J. Hayden

This study uses proteomics to identify biomarkers associated with late maturity alpha-amylase (LMA) in wheat, revealing metabolic and structural changes in LMA-affected grains.

bioRxiv · Jan 22, 2023 · PreprintPlant Biology

Fully Human Antibody Immunoglobulin from Transchromosomic Bovines is Potent Against SARS-CoV-2 Variant Pseudoviruses

T. Luke, H. Wu, K. A. Egland, E. J. Sullivan, C. L. Bausch

This study evaluates the neutralization potency of SAB-185, a fully human antibody immunoglobulin from transchromosomic bovines, against multiple SARS-CoV-2 variants using pseudovirus assays.

bioRxiv · Aug 9, 2021 · PreprintImmunology

Protection of human ACE2 transgenic Syrian hamsters from SARS CoV-2 variants by human polyclonal IgG from hyper-immunized transchromosomic bovines

T. Gilliland, Y. Liu, R. Li, M. Dunn, E. Cottle, Y. Terada, Z. Ryckman, M. Alcorn, S. Vasilatos, J. D. Lundy, D. Larson, H. Wu, T. Luke, C. Bausch, K. Egland, , W. Klimstra

This study evaluates the neutralizing capacity and protective efficacy of human polyclonal IgG against SARS-CoV-2 variants in vitro and in a transgenic hamster model.

bioRxiv · Jul 26, 2021 · PreprintMicrobiology