Efficacy of an oral lipid nanocrystal (LNC) formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis
Y. Gu, T. Gebremariam, S. Alkhazraji, E. Youssef, S. El-Gamal, T. Matkovits, J. Cobb, R. Mannino, A. Ibrahim
This study compares the efficacy of oral MAT2203 to intravenous LAMB in a neutropenic mouse model of mucormycosis, finding MAT2203 as effective in survival and fungal burden reduction.
bioRxiv · Nov 22, 2023Microbiology