Author

T. McBride

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Rajan· 3 shared F. Stossi· 3 shared L. Aideyan· 3 shared P. A. Piedra· 3 shared V. Avadhanula· 3 shared F.-A. Piedra· 2 shared G. M. Aloisio· 2 shared H. L. Johnson· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. Rajan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pediatric human nose organoids demonstrate greater susceptibility, epithelial responses, and cytotoxicity than adults during RSV infection.

G. M. Aloisio, D. Nagaraj, A. M. Murray, E. M. Schultz, T. McBride, L. Aideyan, E. G. Nicholson, D. Henke, L. Ferlic-Stark, A. Rajan, A. Kambal, H. Johnson, E. Mosa, F. Stossi, S. E. Blutt, , V. Avadhanula

This study compares RSV infection responses in pediatric and adult nose organoids, finding pediatric organoids show greater susceptibility, cytokine response, and cellular damage.

bioRxiv · Feb 1, 2024 · PreprintMicrobiology

The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeutics

A. Rajan, A. M. Weaver, G. M. Alosio, J. Jelinski, H. L. Johnson, S. F. Venable, T. McBride, L. Aideyan, F.-A. Piedra, X. Ye, E. Melicoff-Portillo, M. R. K. Yerramilli, X.-L. Zeng, M. A. Mancini, F. Stossi, , P. A. Piedra

This paper develops a non-invasive human nose organoid model to study RSV and SARS-CoV-2 infection and test therapeutics like palivizumab.

bioRxiv · Jul 28, 2021Microbiology

Multiple RSV strains infecting HEp-2 and A549 cells reveal cell line-dependent differences in resistance to RSV infection.

A. Rajan, F.-A. Piedra, L. Aideyan, T. McBride, M. J. Robertson, H. L. Johnson, G. M. Aloisio, D. M. Henke, C. Coarfa, F. Stossi, V. K. Menon, H. Doddapaneni, D. Muzny, S. J. Javornik Cregeen, K. L. Hoffman, , P. A. Piedra

The paper compares RSV infection in HEp-2 and A549 cells using four strains, finding subgroup-dependent gene expression differences and A549's greater antiviral response.

bioRxiv · Jun 15, 2021 · PreprintMicrobiology