Author

F.-A. Piedra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Rajan· 3 shared P. A. Piedra· 3 shared V. Avadhanula· 3 shared A. W. Maresso· 2 shared F. Stossi· 2 shared H. L. Johnson· 2 shared J. F. Petrosino· 2 shared K. L. Hoffman· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMicrobiology

A. Rajan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Progress toward the development of an effective vaccine for Extraintestinal pathogenic E. coli (ExPEC): The application of the multiple-protein subunits vaccine in different murine models

Y. Xing, J. R. Clark, J. D. Chang, J. J. Zulk, D. M. Chirman, F.-A. Piedra, K. A. Patras, A. W. Maresso

This study evaluates pro-HlyA and Dual-Hit as vaccine candidates against ExPEC, showing reduced bacterial burden and increased survival in murine models.

bioRxiv · May 31, 2023 · PreprintMicrobiology

Modeling nonsegmented negative-strand RNA virus (NNSV) transcription with ejective polymerase collisions and biased diffusion

F.-A. Piedra

The paper models NNSV transcription using ejective polymerase collisions and biased diffusion to explain observed mRNA levels in RSV and VSV infections.

bioRxiv · Jun 24, 2022Biophysics

The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeutics

A. Rajan, A. M. Weaver, G. M. Alosio, J. Jelinski, H. L. Johnson, S. F. Venable, T. McBride, L. Aideyan, F.-A. Piedra, X. Ye, E. Melicoff-Portillo, M. R. K. Yerramilli, X.-L. Zeng, M. A. Mancini, F. Stossi, , P. A. Piedra

This paper develops a non-invasive human nose organoid model to study RSV and SARS-CoV-2 infection and test therapeutics like palivizumab.

bioRxiv · Jul 28, 2021Microbiology

Multiple RSV strains infecting HEp-2 and A549 cells reveal cell line-dependent differences in resistance to RSV infection.

A. Rajan, F.-A. Piedra, L. Aideyan, T. McBride, M. J. Robertson, H. L. Johnson, G. M. Aloisio, D. M. Henke, C. Coarfa, F. Stossi, V. K. Menon, H. Doddapaneni, D. Muzny, S. J. Javornik Cregeen, K. L. Hoffman, , P. A. Piedra

The paper compares RSV infection in HEp-2 and A549 cells using four strains, finding subgroup-dependent gene expression differences and A549's greater antiviral response.

bioRxiv · Jun 15, 2021 · PreprintMicrobiology

Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals

H. V. Doddapaneni, S. J. Cregeen, R. Sucgang, Q. Meng, X. Qing, V. Avadhanula, H. Chao, V. Menon, E. Nicholson, D. Henke, F.-A. Piedra, A. Rajan, Z. Momin, K. Kottapalli, K. L. Hoffman, , R. A. Gibbs

This study develops an oligonucleotide capture sequencing method to generate SARS-CoV-2 genomic and transcriptome sequences from clinical samples, revealing differential transcriptional activity and ORF10 expression.

bioRxiv · Jul 27, 2020 · PreprintMicrobiology