MicrobiologybioRxivPreprint
Progressive sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of beta-lactam Resistance without Acquisition of beta-lactamase Genes
J. R. Anderson, N. B. Lam, J. L. Jackson…·T. N. Ellis
This study shows that Klebsiella pneumoniae can develop beta-lactam resistance through mutations without acquiring beta-lactamase genes under progressive sub-MIC cephalothin exposure.
DOI 10.1101/2021.11.19.469034