IL-10 receptor blockade delivered simultaneous with BCG vaccination sustains long term protection against Mycobacterium tuberculosis infection in mice
V. Dwivedi, S. Gautam, C. A. Headley, T. Piergallini, J. B. Torrelles, J. Turner
This study shows that combining BCG vaccination with IL-10 receptor blockade in mice provides long-term protection against M.tb infection, improving T cell responses and survival.
bioRxiv · Sep 5, 2021Immunology