V. Dwivedi

Mitochondrial Transplantation promotes protective effector and memory CD4+ T cell response during Mycobacterium tuberculosis infection and diminishes exhaustion and senescence in elderly CD4+ T cells

This study shows mitochondrial transplantation enhances CD4+ T cell function in elderly individuals and mice infected with Mycobacterium tuberculosis by reducing exhaustion and senescence.

Functional Characterization of Calmodulin-like Proteins, CML13 and CML14, as Novel Light Chains of Arabidopsis Class VIII Myosins

This study identifies CML13 and CML14 as novel light chains of Arabidopsis class VIII myosins through in vivo and in vitro assays.

Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants.

This study identifies a synthetic auxin conjugate that enhances adventitious root formation in recalcitrant woody plants through slow auxin release.

Biochemical analysis of anthocyanin and proanthocyanidin and their regulation in determining chickpea flower and seed coat colours

This study identifies CaMATE1 and CabHLH as regulators of flower and seed coat color in chickpea by manipulating gene expression in a desi genotype.

IL-10 receptor blockade delivered simultaneous with BCG vaccination sustains long term protection against Mycobacterium tuberculosis infection in mice

This study shows that combining BCG vaccination with IL-10 receptor blockade in mice provides long-term protection against M.tb infection, improving T cell responses and survival.

SARS-CoV-2 spike RBD and nucleocapsid encoding DNA vaccine elicits T cell and neutralising antibody responses that cross react with variants

This paper designs a DNA vaccine encoding SARS-CoV-2 spike RBD and nucleocapsid proteins, showing strong T cell responses and cross-reactive neutralizing antibodies against variants in mice.

Rapid and Efficient Inactivation of SARS-CoV-2 from Surfaces using UVC Light Emitting Diode Device

This paper describes a UVC LED device that rapidly inactivates SARS-CoV-2 on surfaces, achieving log10 reductions in viral titers within seconds.

Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging.

This study transfers functional mitochondria into aged CD4+ T cells, improving their metabolism, reducing oxidative stress, and enhancing immune function against infections.

Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice

This study demonstrates that K18 hACE2 transgenic mice are susceptible to SARS-CoV-2 infection, exhibit cytokine and chemokine storms, and serve as a model for studying viral pathogenesis and therapeutic development.

The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required for the release of mRNAs from transcription sites

This study shows UPF1 associates with nascent RNAs in the nucleus and is required for mRNA release from transcription sites in Drosophila.