Cancer BiologybioRxiv
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy
R. C. Geck, J. R. Foley, T. R. Murray Stewart…·A. Toker
This study shows that inhibiting ODC with DFMO sensitizes TNBC cells to chemotherapy, but not receptor-positive breast cancer cells.
DOI 10.1074/jbc.ra119.012376