Author

T. Rakshit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

D. P. Melters· 3 shared Y. Dalal· 3 shared M. Bui· 2 shared C. Andreou· 1 shared D. Senapati· 1 shared D. Sturgill· 1 shared E. K. Dimitriadis· 1 shared G. A. Papoian· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiochemistry

D. P. Melters

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

E-Protein Protonation Titration-induced Single Particle Chemical Force Spectroscopy for Microscopic Understanding and pI Estimation of Infectious DENV

D. Senapati, M. Ghosal, T. Rakshit, S. Bhattacharya, S. Bhattacharyya, P. Satpati

The paper uses chemical force spectroscopy to measure the surface charge dynamics and estimate the isoelectric point of DENV-2 and DENV-4, showing consistency between experimental and theoretical results.

bioRxiv · Mar 30, 2023Biophysics

DNA-functionalized Gold Nanorods for Targeted Triple-modal Optical Imaging and Photothermal Therapy of Triple-negative Breast Cancer

S. Pal, J. K. Koneru, C. Andreou, T. Rakshit, V. Rajasekhar, M. Wlodarczyk, J. H. Healey, M. Kircher, J. Mondal

This paper develops DNA-functionalized gold nanorods for triple-modal optical imaging and photothermal therapy of triple-negative breast cancer, showing preferential tumor accumulation and effective thermal ablation.

bioRxiv · Feb 12, 2022 · PreprintBioengineering

Single Molecule Analysis of CENP-A Chromatin by High-Speed Atomic Force Microscopy

D. P. Melters, K. C. Neuman, T. Rakshit, Y. Dalal

The paper uses high-speed atomic force microscopy to analyze single-molecule dynamics of CENP-A nucleosomes and shows how CENP-C affects their mobility and chromatin accessibility.

bioRxiv · Jan 4, 2022Biophysics

The ratio between centromeric proteins CENP-A and CENP-C maintains homeostasis of human centromeres

D. P. Melters, T. Rakshit, M. Bui, S. A. Grigoryev, D. Sturgill, Y. Dalal

The paper shows that maintaining the CENP-A to CENP-C ratio is critical for centromere homeostasis, as disrupting this balance causes mitotic defects.

bioRxiv · Oct 24, 2019 · PreprintBiochemistry

Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners

D. P. Melters, M. Pitman, T. Rakshit, E. K. Dimitriadis, M. Bui, G. A. Papoian, Y. Dalal

The paper investigates how histone variants encode intrinsic elasticity in nucleosomes and how their binding partners modulate this elasticity and chromatin compaction.

bioRxiv · Jul 10, 2019Biochemistry