Cell BiologybioRxiv
Decreased Colonic Activin Receptor Like Kinase 1 Disrupts Epithelial Barrier integrity and is associated with a poor clinical outcome in Crohns disease
T. Toyonaga, B. P. Keith, J. Barrow…·S. Z. Sheikh
This study identifies ALK1 as a target of miR-31-5p in CD, showing that decreased ALK1 disrupts epithelial barrier integrity and correlates with poor clinical outcomes.
DOI 10.1053/j.gastro.2019.11.133