Cancer BiologybioRxiv
Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia
L. Garnar-Wortzel, T. R. Bishop, S. Kitamura…·M. A. Erb
This study identifies a potent inhibitor of the ENL/AF9 YEATS domain and demonstrates its selective suppression of ENL-dependent leukemia genes.
DOI 10.1021/acscentsci.0c01550